Synonyms: 1,2:5,6-bis-O-(1-methylethylidene)-3-O-(phenylmethyl)- a-D-Glucofuranose; 1,2:5,6-di-O-isopropylidene-3-O-benzyl-α-D-Glucofuranose; 3-O-benzyl-1,2:5,6-di-O-isopropylidene-D-Glucofuranose; Furo[2,3-d]-1,3-dioxole, a-D-glucofuranose deriv.
Molecular Formula: C19H26O6
Molecular weight: 350.4061
CAS No.: 18685-18-2
Quality Standard:
| Item |
Specification |
| Appearance |
Sticky liquid of yellow to wine red |
| Assay (HPLC), % |
≥98 |
| Specific rotation (C=1.0,CHCl3) |
--24.5~-28.5 |
Characteristics: This product is a sticky liquid of yellow to wine red. It soluble in ethanol, chloroform, dichloromethane, ethyl acetate, and ethyl ether, etc., insoluble in water.
Uses: The product is an important materials and intermediates of pharmaceuticals. As start material which mainly used in synthesis anticancer agent Goniofufurone, brain-tumor inhibitor 2-deoxy-2,2-difluoro-D-arabino-hexopyranose, activated precursors of oligonucleotides (9-(3'-O-benzyl-2'-O-benzyloxycarbonyl)β-D-xylofuranosyl) adenine, glycosidase inhibitor nojirimycin, HIV inhibitor 1,4-Dideoxy-1,4-imino-D-arabinitol, anti-inflammatory agent such as glycosylated indole, (-) - Dinemasone B, phosphatidyl-myo-inostiol mannoside analogues, and glycosylated asterosaponin with mult-pharmacological activities, etc.. It used in synthesis following pharmaceutica intermediate 2,4,6-tri-O-benzoyl-3-O-benzyl glucopyranosyl imidate for glucan-hexasaccharide vaccines, 3-O-benzyl-1,2-O-isopropylidene-α-L-idofuranose for Fondaparinux sodium, and 3-O-Benzyl-1,2-O-isopropylidene-α-xylo-pentodialdofuranose for anthracyclinone. The product also used in synthesis its following derivatives 3-O-benzyl-1,2-O-isopropylidene-D-glucofuranose, 3-O-benzyl-D-glucofuranose, α,β-D-Methyl glucopyranoside, 2,5, 6-tri-O-methyl-D-glucofuranose, 3-O-benzyl-xylitol, 3,4-di-O-methyl-D-erythritol, 2,4,6-Tri-O-methyl-D-mannose, L-idose, 6-deoxy-6-Acetamido-L-idothiapyranose, 6-O-benzoyl-l,2-O-isopropylidene-D-glucofuranose,3-O-benzyl-4,6-benzylidene-D-glucofuranose, 3-O-benzyl-1,2-isopropylidene-α-D-glucopyranoic acid, Methyl-3-O-Benzyl-5,6-di-O-isopropyIidene-α,β-D-glucofuranoside and so on. In addition, the product also is a kind of chiral auxiliary for some organicreaction and synthon for oligosaccharides and glycopolymer
Storage: Maintain in cool, dry containment.
Package: 25kg/drum or as customer require.
Expiration Date: 2 years
